Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ VU 0463271
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Potent and selective KCC2 inhibitor
| Target | KCC2 Inhibitors |
|---|---|
| CAS | 1391737-01-1 |
| Purity | >98% |
| Chemical Name or Material | N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H18N4OS2 |
| Formula Weight | 382.5 |
Tocris Bioscience™ Cabergoline
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CAS: 81409-90-7 Molecular Formula: C26H37N5O2
| CAS | 81409-90-7 |
|---|---|
| Molecular Formula | C26H37N5O2 |
Tocris Bioscience™ TY 52156
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S1P3 receptor antagonist
| Product Type | TY 52156 |
|---|---|
| Molecular Weight (g/mol) | 364.27 |
| Purity | >98% |
Tocris Bioscience™ (R)-DRF053 dihydrochloride
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Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
| Inhibitors | (R)-DRF053 dihydrochloride |
|---|---|
| Product Type | (R)-DRF053 dihydrochloride |
| Molecular Weight (g/mol) | 490.43 |
| Purity | >98% |
Tocris Bioscience™ Glycyl-H 1152 dihydrochloride
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CAS: 913844-45-8 Molecular Formula: C18H26Cl2N4O3S
| CAS | 913844-45-8 |
|---|---|
| Molecular Formula | C18H26Cl2N4O3S |
Tocris Bioscience™ CP 376395 hydrochloride
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Potent and selective CRF1 antagonist; binds at an allosteric site
| Inhibitors | CP 376395 hydrochloride |
|---|---|
| Product Type | CP 376395 hydrochloride |
| Molecular Weight (g/mol) | 362.94 |
| Purity | >99% |
| CAS | 56425-91-3 |
|---|---|
| Molecular Formula | C15H15F3N2O2 |
Tocris Bioscience™ Arctigenin
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CAS: 7770-78-7 Molecular Formula: C21H24O6
| CAS | 7770-78-7 |
|---|---|
| Molecular Formula | C21H24O6 |
Tocris Bioscience™ Thalidomide 4'-ether-alkylC3-azide
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
Tocris Bioscience™ TGN 020
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Aquaporin 4 (AQP4) channel blocker
| Inhibitors | TGN 020 |
|---|---|
| Product Type | TGN 020 |
| Molecular Weight (g/mol) | 206.22 |
| Purity | >99% |
Tocris Bioscience™ Ipsapirone
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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CAS: 95847-70-4 Molecular Formula: C19H23N5O3S
| CAS | 95847-70-4 |
|---|---|
| Molecular Formula | C19H23N5O3S |
Tocris Bioscience™ 8MDP
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Potent equilibrative nucleoside transporter (ENT) inhibitor
Tocris Bioscience™ 5-Iodotubercidin
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CAS: 24386-93-4 Molecular Formula: C11H13IN4O4
| CAS | 24386-93-4 |
|---|---|
| Molecular Formula | C11H13IN4O4 |
Tocris Bioscience™ RepSox
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RepSox synthesized to Ancillary Material Grade
Tocris Bioscience™ EN6
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H+ ATPase activator; activates autophagy; inactivates mTORC1 signaling
| Target | H+-ATPase Inhibitors |
|---|---|
| CAS | 1808714-73-9 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-Fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1 H-pyrazole-4-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H14F2N4O2 |